Microlife
Microlife is a fairly cool Kerb designed Flash game/tie-in with BBC children's show Blue Peter, in which you tend to a tamagotchi esque colony of little herpes creatures, and attempt to shepherd them through the rigors of life until they're all grow'd up enough to leave the planet.
Microlife (seen @ Metafilter)
Presviously with Kerb :
Panik In Chocoland